Rule out other disorders.
Don’t assume that your symptoms are due to IBS unless your doctor has told you so. You need to get a thorough medical workup to rule out other, more serious conditions, including Crohn’s disease, ulcerative colitis, celiac disease, and colorectal cancer. Even if you’ve had a diagnosis of IBS, be sure to go back to your doctor if your symptoms change or worsen.

Talk with your doctor about medications.

Talk with your doctor about medications.
The first line of treatment for IBS is typically diet and lifestyle changes. But if you can’t get your symptoms under control, and if the pain and other symptoms are affecting your life, ask your doctor about medications that have been approved for IBS. There are a variety of possible medications, including antispasmodics, antidiarrheals, and antidepressants. Yes, antidepressants — because they seem to modulate intestinal pain and regulate gut function. Many antidepressants regulate the neurotransmitter serotonin and — surprisingly — 95 percent of serotonin is found in your gut, where it helps maintain smooth, regular contractions of the intestines. Some scientists believe that in people with IBS, the intestines aren’t getting enough serotonin. More research needs to be done before antidepressants are a first-line treatment, but if you’ve tried everything else, you may want to discuss this possibility with your physician.